Advancing peptide therapeutics,
one residue at a time.
From first binder to GMP manufacturing, we help pharmaceutical and biotech teams take peptide candidates all the way, with the chemistry, analytics and process know-how to move quickly and get it right.
NewFree peptide calculator: mass, pI and synthesis complexity→
A focused peptide partner with a proven pharmaceutical foundation.
SMS Peptides Private Limited is a specialised subsidiary of SMS Pharmaceuticals, dedicated entirely to peptide therapeutics. We bring together discovery, synthetic chemistry, analytical science, process development and GMP manufacturing so partners can move from first binder to clinical supply with one team.
Our parent company’s manufacturing experience and quality culture shape how we work: reproducible results, realistic timelines and clear communication at every stage.
Read our story →-
Peptide focus
Every chemist and analyst on our team works on peptides, and nothing else.
-
Scientific depth
Drug discovery experience from Sweden, Israel and India.
-
Quality first
Pharmaceutical-grade systems, built on a heritage since 1987.
-
Long-term partnership
We plan for your next milestone, not just the current order.
From first binder to GMP manufacturing.
Five connected steps take your program from target to medicine. Each step hands its result straight to the next, with one partner and no hand-offs.
Discovery
AI-designed libraries screened by phage display find the first peptides that bind your target.
Explore → 02Binder → hitsSynthesis & libraries
We resynthesise the binders and their variants, including cyclic, stapled and conjugated forms, to confirm real hits.
Explore → 03Hit → leadHit-to-lead & lead optimisation
SAR, analogue design and stability studies, with partner biology when needed, improve potency and drug-like properties until you have a lead.
Explore → 04Lead → processProcess & analytical development
Process research, impurity standards and analytical methods make the lead’s route robust and ready to transfer to GMP.
Explore → 05Process → GMP APIGMP manufacturing
Multi-kilogram peptide API made under GMP at our USFDA, EU-GMP and WHO-GMP approved Vizag site, for clinical and commercial supply.
Explore →Unit 7, Visakhapatnam.
We manufacture within SMS Pharmaceuticals’ flagship API site, inspected by the USFDA and approved by EU-GMP, WHO-GMP, PMDA and KFDA. A dedicated peptide plant is coming up on the site.
See the site and video →
Peptide plant coming up here
One CDMO partner across all five steps.
Whether you need one compound or a long-term supply partner, one team knows your molecule from the first binder onwards.
Flexible engagement
Fee-for-service projects, dedicated scientist teams, or integrated development-and-supply programs.
One project lead
A single point of contact, clear milestones and regular progress reports at every step.
Confidentiality & IP
We work under NDA, and the process we develop for your molecule stays yours.
Regulatory-ready documents
Development reports, batch records and quality data to support your regulatory filings.
Typical quantities at each step, up to multi-kilogram GMP API every month.
- Discovery
- Synthesis
- Lead opt.
- Process dev.
- GMP
Small enough to design. Powerful enough to matter.
Peptides combine the selectivity of biologics with the synthetic flexibility of small molecules. More than 100 peptide drugs are approved worldwide, with hundreds more in clinical development.
Precise targeting
Engage specific receptors and protein–protein interactions that small molecules struggle to reach.
Synthetic flexibility
Modern SPPS and solution-phase methods make diverse libraries and scalable routes practical.
Engineered stability
D-amino acids, N-methylation, stapling, cyclisation and conjugation extend half-life.
Favourable safety
Peptides break down into natural amino acids, lowering the risk of toxic metabolites.
Broad therapeutic reach
Growing pipelines in metabolic disease, oncology, cardiovascular and rare disease.
Proven path to market
Industry experience with complex molecules has lowered the barriers to peptide development.
Peptide calculator.
Paste any sequence to get its mass and isoelectric point instantly, and see how hard it will be to make by solid-phase synthesis.
- Monoisotopic and average mass, formula and LC-MS ions
- Isoelectric point (pI) and net charge across pH 0–14
- Hydrophobicity (GRAVY) and beta-sheet propensity
- Aggregation-prone regions and sequence liabilities
- Water solubility guide with a suggested solvent
- Synthesis complexity score with practical suggestions
Smarter libraries. Better hits with every cycle.
We are building an integrated hit identification platform where AI-designed libraries meet phage display, and real binding data shapes the next library.
Platform in development: enquire about early collaborationsAI library design
Target analysis predicts high-affinity sequences before any wet-lab work.
Phage display panning
Three to five rounds of selection enrich binders against the target.
Hit identification
NGS, ELISA and SPR confirm the strongest binders.
Lead optimisation
SAR, cyclisation and stapling improve potency and stability.
Binders and non-binders from each round feed back into the model, so every library is more focused than the last.
How the platform works →Move the right molecule forward.
Tell us about your target, sequence or challenge. Our scientific team will help you plan the right next step.